Five types of lymphocytes (lg− θ−, lg− θ+ weak, lg− θ+strong, lg+ θ− and lg+ θ+) characterized by double immunofluorescence and electrophoretic mobility Organ distribution in normal and nude mice

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Abstract
The simultaneous detection of Ig and θ on the surface of mouse lymphocytes permits the detection of four cell types (Ig−θ−, Ig−θ+, Ig+θ−, and Ig+θ+) which also have distinct electrophoretic profiles. All types are present in variable proportions in all lymphoid organs studied. Results obtained in congenitally athymic nude mice and in T-deprived mice define a new type of lymphocyte, the Ig−θ+weak. This cell is non-recirculating, Ig−, with a low density of θ and a slow electrophoretic mobility. It is a candidate for a T-committed prethymic cell.