A Study of Experimental Hypercholesterolemia in the Mouse

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Abstract
In cholic acid-induced hypercholesterolemia in the mouse the following substances were observed to produce a plasma cholesterol-depressing effect: cod liver oil, hexaenoic acid concentrate, tung oil, estradiol, cystine, cysteine hydrochloride and taurine. Tung oil was effective only at a dietary level that produced a growth inhibition. Dietary taurine eliminated the hypocholesterolemic effect of cystine and cysteine hydrochloride. Oleic acid and a hydrogenated coconut oil enhanced the hypercholesterolemic effect of cholic acid.