Inhibitors of sterol synthesis. An efficient and specific side chain oxidation of 3β-hydroxy-5α-cholest-8(14)-en-15-one. Facile access to its metabolites and analogs.

This publication has 13 references indexed in Scilit:

• Inhibitors of sterol synthesis
  Published by Elsevier ,1989
• Synthesis of zymosterol, fecosterol, and related biosynthetic sterol intermediates
  Journal of the American Chemical Society, 1989
• Inhibitors of sterol synthesis. Studies of the metabolism of 5α-cholest-8(14)-en-3β-ol-15-one in Chinese hamster ovary cells and its effects on activities of early enzymes in cholesterol biosynthesis
  Chemistry and Physics of Lipids, 1988
• Concerning the chemical synthesis of 3β-hydroxy-5α-cholest-8(14)-en-15-one, a novel regulator of cholesterol metabolism
  Chemistry and Physics of Lipids, 1988
• Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5α-cholest-8(14)-en-3β-ol-15-one in rat liver preparations
  Chemistry and Physics of Lipids, 1988
• 5α-Cholest-8(14)-EN-3β-OL-15-one. A competitive substrate for acyl coenzyme a:Cholesterol acyl transferase
  Biochemical and Biophysical Research Communications, 1987
• Inhibitors of sterol synthesis. Effect of dietary 5α-cholest-8(14)-EN-3β-OL-15-one on acat activity of jejunal microsomes of the rat
  Biochemical and Biophysical Research Communications, 1987
• Inhibitors of sterol synthesis. Dietary administration of 5α-cholest-8(14)-en-3β-ol-15-one inhibits the intestinal absorption of cholesterol in lymph-cannulated rats
  Biochemical and Biophysical Research Communications, 1987
• 5 alpha-Cholest-8(14)-en-3 beta-ol-15-one lowers serum cholesterol and induces profound changes in the levels of lipoprotein cholesterol and apoproteins in monkeys fed a diet of moderate cholesterol content.
  Proceedings of the National Academy of Sciences, 1984
• Functionalization of steroid side chains: conversion of cholesterol to chol-5-ene-3.beta.,24-diol
  The Journal of Organic Chemistry, 1979