The Architecture of Diagnostic Research

• 10 October 2008
• book chapter
• Published by Wiley
• p. 20-41
• https://doi.org/10.1002/9781444300574.ch2

Abstract

Keywords

• ARCHITECTURE OF DIAGNOSTIC RESEARCH
• NORMAL OR GAUSSIAN DISTRIBUTION
• PUTATIVE DIAGNOSTIC TEST OR BNP
• TARGET DISORDER AND DIFFERENT TEST RESULTS
• ANSWERING A PHASE II QUESTION
• ANSWERING A PHASE III QUESTION WITH LIKELIHOOD RATIOS
• THREATS TO VALIDITY OF PHASE III STUDIES
• VALIDITY OF ACCURACY ESTIMATES GENERATED IN PHASE III STUDIES
• LIMITATION OF PHASE V STUDIES