MALIGNANT CHORDOMA OF THE LUMBAR REGION
- 1 March 1928
- journal article
- other
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 19 (3) , 415-423
- https://doi.org/10.1001/archneurpsyc.1928.02210090041003
Abstract
The origin of chordomas in the chorda dorsalis has been definitely established. Virchow1was the first to describe such tumors and thought that he was dealing with cartilaginous formations. He termed these growths found at the spheno-occipital synchondroses "ecchondrosis physaliphora." Müller2first advanced the view that the tumor originated from the notochordal cells. His observations were not accepted definitely until 1895, when Ribbert3experimentally produced chordomas by puncturing anteriorly the intervertebral disks of rabbits. He thus definitely proved that chordomas originate from the notochord. The histogenesis and the evolution of the tumors were first described in detail by Alezius and Peyron.4The clinical symptoms of the clivus were first noted by Klebs.5Fischer6was the first to describe malignant chordoma of the skull, and Mazzia7was the first to describe malignant chordoma of the sacrococcygeal region. A complete review of the subject hasKeywords
This publication has 1 reference indexed in Scilit:
- MALIGNANT SPHENO-OCCIPITAL CHORDOMAJournal of Nervous & Mental Disease, 1925