Pupillary Effects of Levodopa Therapy

Abstract
In a patient with Parkinson's disease and subclinical postganglionic Horner's syndrome anisocoria developed during chronic oral L-dopa therapy. This provided an opportunity to investigate the mechanism of action of L-dopa and dopamine on the sympathetic innervation of the eye. Five patients, one of whom had a postganglionic Horner's syndrome without Parkinson's disease, served as controls.