Sotos syndrome — autosomal dominant inheritance substantiated
- 1 September 1985
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 28 (3) , 243-246
- https://doi.org/10.1111/j.1399-0004.1985.tb00393.x
Abstract
Sotos syndrome, or Cerebral Gigantism is recognized as the syndromic association of mental retardation, macrocephaly and prenatal onset of accelerated growth. A kindred has been investigated in which the father and 4 affected offspring all have the Sotos syndrome. Autosomal dominant inheritance has been postulated in the past, and the family conform to this genetic pattern.Keywords
This publication has 5 references indexed in Scilit:
- INVESTIGATIONS IN DOMINANT SOTOS SYNDROME1981
- Dominant inheritance of cerebral gigantismThe Journal of Pediatrics, 1977
- FAMILIAL OCCURRENCE OF CEREBRAL GIGANTISM, SOTOS' SYNDROMEActa Paediatrica, 1976
- Evidence for autosomal recessive inheritance in cerebral gigantismJournal of Medical Genetics, 1974
- Cerebral Gigantism in ChildhoodNew England Journal of Medicine, 1964