Protection by Cepharanthie of the Mitochondrial Function from Damage Induced by Snake Venom, Phospholipase A2, Lysolecithin and Lead

Abstract
The action of cepharanthie, a biscoclaurine alkaloid, on disturbances of the [Wistar rat liver] mitochondrial function caused by snake venom, phospholipase A2, lysolecithin, Pb and high temperature was examined. The alkaloid protected mitochondria from damage caused by these treatments. The alkaloid protects biomembranes from various kinds of damage with no effect of its own at a low concentration.

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