ANALGESIC EFFECT OF APROTININ IN THE RAT AND ITS INHIBITION BY NALOXONE
Open Access
- 1 November 1980
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 52 (11) , 1107-1110
- https://doi.org/10.1093/bja/52.11.1107
Abstract
Experiments were performed on rats using two analgesimetric tests (tail-flick; hot-plate) before and after injection i.v. of graded doses of apruunin (12.5, 25.0 and 50 KIU g−1). A dose-related analgesic effect was noted with both tests. Prior administration of naloxone 0.001 mg g−1 i.p. inhibited the analgesic action.Keywords
This publication has 1 reference indexed in Scilit: