Effects of weight loss on the dexamethasone suppression test
- 1 March 1983
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 140 (3) , 338-341
- https://doi.org/10.1176/ajp.140.3.338
Abstract
The authors studied postdexamethasone cortisol secretion in 18 depression-free, healthy, obese subjects before and after weight loss. Although all subjects suppressed cortisol normally before weight loss, 5 of 18 (27.5%) failed to suppress cortisol after an average loss of 13.5 kg. This failure to suppress cortisol was not associated with any change in depression ratings.Keywords
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