INFLUENCE OF SEX ON FETAL RABBIT LUNG MATURATION AND ON THE RESPONSE TO GLUCOCORTICOID
- 1 January 1980
- journal article
- research article
- Published by Elsevier
- Vol. 121 (2) , 377-380
- https://doi.org/10.1164/arrd.1980.121.2.377
Abstract
Female premature rabbit fetuses had more stable lungs than male premature rabbit fetuses. In male and female rabbit fetuses, deflation stability increased to a similar extent after administration of glucocorticoid, but the resultant male lungs were significantly less stable. The lungs of female fetuses treated with steroid had greater histologic maturity than those of male fetuses, with a higher proportion of air space and thinner airspace walls after completion of pressure-volume studies. Apparently sex differences must be considered in studies of lung maturation.This publication has 3 references indexed in Scilit:
- Fetal rhesus monkey lung development: lobar differences and discordances between stability and distensibilityJournal of Applied Physiology, 1977
- Birth weight, gestational age, and sex asdetermining factors in the incidence of respiratory distress syndrome of prematurely born infantsThe Journal of Pediatrics, 1968
- A principle for counting tissue structures on random sectionsJournal of Applied Physiology, 1962