The significance of anti-Müllerian hormone concentration in seminal plasma for spermatogenesis.
Open Access
- 1 April 2002
- journal article
- research article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 17 (4) , 968-970
- https://doi.org/10.1093/humrep/17.4.968
Abstract
BACKGROUND: The function of anti-Müllerian hormone (AMH) in seminal plasma in adulthood is uncertain. We examined the significance of seminal AMH for spermatogenesis. METHODS: We measured seminal concentrations of AMH in 39 oligozoospermic men (mean age ± SD, 32.7 ± 4.3 years) and 10 normal volunteers to examine the association of seminal AMH with spermatogenesis. The seminal concentrations of AMH in oligozoospermic men (149.3 ± 254.0 pmol/l) were significantly lower than in normal men (249.0 ± 167.7 pmol/l; P ± 0.0337). Seminal AMH concentration correlated significantly with sperm concentration (r = 0.339, P = 0.0350) and mean testicular volume (r = 0.440, P = 0.246). The serum concentration of LH (r = – 0.365, P = 0.0241), but not FSH, testosterone or estradiol, correlated significantly with AMH concentration in seminal plasma. CONCLUSIONS: AMH in seminal plasma may be important for sperm production, and is a good marker for Sertoli cell development.Keywords
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