Insulin Effect on Proteolytic Activities in Rat Skeletal Muscle
- 1 March 1978
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 10 (02) , 101-104
- https://doi.org/10.1055/s-0028-1093452
Abstract
Proteolytic activity has been measured in rat skeletal muscle by use of [14C]-hemoglobin as substrate. The activity of the alkaline proteinases increases during starvation and in diabetic state. In streptozotocin-diabetic animals the activity of alkaline proteases increases to 300% over a time of 21 days. Insulin treatment reverses the enhanced enzyme activity to normal level.Keywords
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