Human T cell specific proteinase (HuTSP) is encoded by the T cell and natural killer cell specific human Hanukah factor (HuHF) gene
- 12 September 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 237 (1-2) , 45-48
- https://doi.org/10.1016/0014-5793(88)80168-6
Abstract
HuTSP, a serine proteinase which is specifically associated with activated T lymphocytes, was purified to homogeneity and characterized. N-terminal amino acid sequencing revealed identity with a sequence predicted from the human Hanukah factor (HF) gene, which was isolated from a human T cell cDNA library. The dimeric structure of HuTSP, together with its extensive sequence homologies with the murine T cell specific proteinase, MTSP-1, suggests phylogenetic conservation of this serine proteinase familyKeywords
This publication has 20 references indexed in Scilit:
- Induction of T cell serine proteinase 1 (TSP‐1)‐specific mRNA in mouse T lymphocytesEuropean Journal of Immunology, 1988
- Proposed classification of leukocyte- associated cytolytic moleculesImmunology Today, 1987
- Are proteinases functional molecules of T lymphocytes?Immunology Today, 1987
- Identification of granzyme A isolated from cytotoxic T‐lymphocyte‐granules as one of the proteases encoded by CTL‐specific genesFEBS Letters, 1986
- Isolation and characterization of a serine esterase from cytolytic T cell granulesCell, 1986
- Serine esterase in cytolytic T lymphocytesNature, 1986
- Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T LymphocyteScience, 1986
- Factors Affecting B-Cell Growth and DifferentiationAnnual Review of Immunology, 1985
- The molecular mechanism of lymphocyte-mediated tumor cell lysisImmunology Today, 1985
- Interleukin 2Annual Review of Immunology, 1984