Methylthiomethyl Esters (II) Transesterification and Amide Formation
- 1 January 1973
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 3 (2) , 145-146
- https://doi.org/10.1080/00397917308062023
Abstract
Recently the preparation and the hydrolytic properties of methylthiomethyl esters (1) were described.1 However, the question of whether water attacks the acyl or the alkyl carbon atom during the process of neutral hydrolysis remained unsettled. We now wish to provide evidence in favor of an acyl cleavage pathway, and further outline some synthetic applications of this class of compounds.Keywords
This publication has 1 reference indexed in Scilit:
- Dethioacetalization via S-MethylationSynthesis, 1972