• 1 January 1981
    • journal article
    • research article
    • Vol. 123  (3) , 265-268
Abstract
Pneumococcal bacteremia was evaluated retrospectively for 3.5 yr. Of 63 episodes occurring in 62 patients, 37 were nosocomial in origin and 26 were community-acquired. Pneumococcal bacteremia was most common between Jan.-June. Patients with nosocomial disease had significantly more ultimately fatal disease and sustained more manipulation of the respiratory tract than patients with community-acquired bacteremia. The mortality of nosocomial pneumococcal bacteremia (75.8%) or nosocomial pneumococcal pneumonia with bacteremia (66.7%) was significantly > community-acquired bacteremia (26.9%; P < 0.01) or pneumonia with bacteremia (18.2%; P < 0.001). All 62 patients were eligible for pneumococcal vaccine, and 57 could have received immunoprophylaxis. A vaccine trial is indicated in the hospital setting.