24-Hour Periodicity and Audiogenic Convulsions in I Mice of Various Ages.

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Abstract
The daily rhythms in eosinophil count and in rectal temperature are described for I mice and significant age and sex differences in rectal temperature are noted. Furthermore, 24-hour periodicities are noted for the susceptibility of I mice to audiogenic convulsions and for their ability to recover from convulsions. In one group of young I mice the convulsive risk was 11% by day and 63% by night and in another, 0% by day and 85% by night. Of the 27 mice convulsing by night none recovered from seizure while 3 of the 4 mice convulsing by day did recover. A decrease, with advancing age, of the susceptibility of I mice to convulsions is also recorded.