STUDIES OF LIPOPROTEIN-LIPASE ACTIVITY AND ADIPOCYTE CHARACTERISTICS IN HUMAN - EFFECT OF OBESITY AND DIABETES

  • 1 January 1976
    • journal article
    • research article
    • Vol. 2  (1) , 5-9
Abstract
Adipose tissue lipoprotein lipase activity (LPLA) and cellularity were studied in controls, in diabetic or non-diabetic obese subjects and in insulin-dependent diabetic patients. LPLA is increased in diabetic or non-diabetic obese subjects (P < 0.02) and decrease in insulin-dependent diabetic patients (P < 0.02). Adipocyte size is larger in obese subjects, whether diabetic or not (P < 0.05). As defined by LPLA and cell size means, the different groups are related linearly. The implications of this relationship between LPLA and adipocyte size are considered.