Pentagastrin Analogs Containing α-Aminooxy Acids, I Synthesis of Analogs Substituted at the N-Terminus
- 1 January 1978
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 359 (2) , 887-896
- https://doi.org/10.1515/bchm2.1978.359.2.887
Abstract
New pentagastrin analogs [9] containing a free or protected .alpha.-aminooxy acid at the N-terminus were synthesized stepwise. Analogs containing leucyl, norleucyl, norvalyl, L- and D-2-aminodecanoyl residues instead of methionyl residue were also prepared. The peptides were synthesized by the active ester method with subsequent removal of the protecting groups. The purification of the end products was performed by crystallization or column chromatography on silica gel.This publication has 14 references indexed in Scilit:
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