Osteocalcin and bone morphometric parameters in adults without bone disease
- 1 January 1988
- journal article
- research article
- Published by Springer Nature in Calcified Tissue International
- Vol. 42 (1) , 13-17
- https://doi.org/10.1007/bf02555833
Abstract
Serum bone Gla-protein (s-BGP or osteocalcin) and other serum biochemical parameters were measured in 19 subjects (8 women and 11 men, aged 20–82 years) without any bone disease. Each subject simultaneously underwent an iliac crest biopsy; tetracycline double-labeling was performed in 11 subjects, allowing correlations between s-BGP and bone histomorphometric parameters. s-BGP was significantly correlated with static bone parameters: trabecular bone volume (r=0.74;PPPPP<0.01). We conclude that s-BGP is a valuable marker for evaluating bone formation in healthy adult subjects.This publication has 29 references indexed in Scilit:
- Serum bone gamma carboxyglutamic acid-containing protein in primary hyperparathyroidism and in malignant hypercalcemia. Comparison with bone histomorphometry.Journal of Clinical Investigation, 1986
- PLASMA OSTEOCALCIN IN MANAustralian and New Zealand Journal of Medicine, 1985
- Plasma levels of bone Gla-protein reflect bone formation in patients on chronic maintenance dialysisKidney International, 1984
- DIFFERENCES IN SERUM BONE GLA PROTEIN WITH AGE AND SEXThe Lancet, 1984
- Evidence for Defective Osteoblastic Function A Role for Alcohol and Tobacco Consumption in Osteoporosis in Middle-aged MenPublished by Wolters Kluwer Health ,1983
- Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss.Journal of Clinical Investigation, 1983
- Measurements of γ-carboxyglutamate and circulating osteocalcin in normal children and adultsClinica Chimica Acta; International Journal of Clinical Chemistry, 1983
- Carboxylated Calcium-Binding Proteins and Vitamin KNew England Journal of Medicine, 1980
- Tetracycline double-labeling of iliac trabecular bone in 41 normal adultsCalcified Tissue International, 1978
- Mean wall thickness of trabecular bone packets in the human iliac crest: Changes with ageCalcified Tissue International, 1978