Abstract
Report of a case of pheochromocytoma with sustained hypertension; tachycardia; hyperhidrosis; fall of the blood pressure to normal levels during hyperventilation; basal metabolic rates as high as +142%; hypothalamic manifestations, such as hyperthermia, polyuria, polydipsia and polyphagia, occasional glycosuria and acetonuria, acrocyanosis, vascular retinopathy, and impaired kidney function. All pathologic phenomena disappeared promptly after removal of the tumor. The pathogenic role of sympathomimetic neurohormones (epinephrine, nor-epinephrine) in pheochromocytoma-induced and essential hypertension is briefly discussed.