EFFECTS OF INTERFERON ON C1300 MOUSE NEURO-BLASTOMA

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  • 1 January 1982
    • journal article
    • research article
    • Vol. 66  (7) , 1575-1577
Abstract
The effects of murine interferon (MuIFN) with and without cyclophosphamide (CY) were evaluated in C1300 neuroblastoma-bearing mice. Mean survival times were prolonged by administration of 25,000 IU of MuIFN 3 times/wk by i.p. injection. The combination of MuIFN and CY was more effective in the treatment of mouse neuroblastoma than either agent alone. MuIFN could be synergistic in combination with moderate amounts of CY in mouse neuroblastoma cells and may be given for the treatment of neuroblastoma.

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