Seroconversion to HCoV-NL63 in Rhesus Macaques
Open Access
- 29 October 2009
- Vol. 1 (3) , 647-656
- https://doi.org/10.3390/v1030647
Abstract
HCoV-NL63 is a recently identified respiratory virus. Its pathogenesis has not been fully unraveled because an animal model is currently lacking. Here we examined whether rhesus macaques encounter HCoV-NL63 infections during life, by examining the levels of antibodies to HCoV-NL63 in time. The animals were followed for 7 up till 19 years, and in three animals we observed a steep rise in antibodies during follow up, indicative of a natural infection with HCoV-NL63.Keywords
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