Regioselective N-Alkylation in 5-Fluorouracil.
- 1 January 1979
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 33b (7) , 515-518
- https://doi.org/10.3891/acta.chem.scand.33b-0515
Abstract
5-Fluorouracil [an antineoplastic drug] was alkylated selectively on N-1 via its 4-methylthio derivative. Similarly N-3 alkylation was achieved via the 2-methylthio derivative of 5-fluorouracil.This publication has 1 reference indexed in Scilit:
- Nonclassical Antimetabolites XXIVJournal of Pharmaceutical Sciences, 1965