Radionuclide imaging of lipoma and liposarcoma.

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Abstract
Radionuclide imaging with Tc-99m phosphate compounds was performed in 18 patients with deep-seated soft-tissue masses. The histologically established diagnosis was intra- or intermuscular lipoma in 13 patients and liposarcoma in 5. Radionuclide scans demonstrated disparate scintigraphic characteristics in these 2 often clinically similar lesions. Soft-tissue radionuclide accumulation occurred in 2 lipomas and corresponded to radiographically evident calicification. All liposarcomas were uncalcified and demonstrated intense radionuclide activity. This activity may be related to the angiographic and histologic hypervascularity of liposarcomas, which is also demonstrable on computed tomography as contrast enhancement; hence, these modalities offer the same nonspecific diagnostic information. Plain radiography and radionuclide scanning should suffice to establish the diagnosis of lipoma.

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