TERMINATION OF PREGNANCY WITH VAGINAL ADMINISTRATION OF 16, 16 DIMETHYL PROSTAGLANDIN E2 p‐BENZALDEHYDE SEMICARBAZONE ESTER
- 1 February 1977
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 84 (2) , 135-137
- https://doi.org/10.1111/j.1471-0528.1977.tb12540.x
Abstract
A 16,16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester was used for termination of pregnancy in 54 late first trimester and second trimester patients. The drug (750 microng in gelatine glycerine pessaries) was administered every four hours. Fifty patients (92-5%) aborted during the 36 hours treatment. Side effects were mild and consisted of vomiting in five patients, diarrhoea in three patients and transient pyrexia in two.Keywords
This publication has 3 references indexed in Scilit:
- Abortifacient action of orally administered 16, 16 dimethyl prostaglandin E2 and its methyl esterProstaglandins, 1974
- Effect of prostaglandin 16,16 dimethyl E2 methyl ester on the pregnant human uterusProstaglandins, 1973
- The effect of orally and intravenously administered prostaglandin 16:16 dimethyl E2 methyl ester on human gastric acid secretionProstaglandins, 1973