Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin
Open Access
- 13 May 2010
- journal article
- Published by American Society of Hematology in Blood
- Vol. 115 (19) , 3907-3915
- https://doi.org/10.1182/blood-2009-09-244251
Abstract
Many B-cell chronic lymphocytic leukemia (CLL) monoclonal antibodies (mAbs) can be grouped into subsets based on nearly identical stereotyped sequencKeywords
This publication has 47 references indexed in Scilit:
- Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIABlood, 2008
- IMGT(R), the international ImMunoGeneTics information system(R)Nucleic Acids Research, 2008
- Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cellsHaematologica, 2008
- CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cellsBlood, 2007
- Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informaticsJournal of Clinical Investigation, 2007
- Actin‐binding protein filamin A is displayed on the surface of human neuroblastoma cellsCancer Science, 2006
- The role of IgM antibodies in the recognition and clearance of apoptotic cellsMolecular Immunology, 2005
- Cleavage of Nonmuscle Myosin Heavy Chain-A during Apoptosis in Human Jurkat T CellsThe Journal of Biochemistry, 2005
- Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic LeukemiaThe Journal of Experimental Medicine, 2004
- ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profileBlood, 2003