Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
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- 1 March 2008
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 15 (3) , 234-245
- https://doi.org/10.1016/j.chembiol.2008.02.010
Abstract
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This publication has 35 references indexed in Scilit:
- RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channelsNature, 2007
- Selective inhibitors of death in mutant huntingtin cellsNature Chemical Biology, 2006
- Discovery and development of sorafenib: a multikinase inhibitor for treating cancerNature Reviews Drug Discovery, 2006
- Voltage-dependent anion channel (VDAC) as mitochondrial governator—Thinking outside the boxBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006
- The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and CancerPharmacological Reviews, 2005
- Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymeraseNature, 2005
- The ferritins: molecular properties, iron storage function and cellular regulationPublished by Elsevier ,1999
- Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE AlgorithmJNCI Journal of the National Cancer Institute, 1989
- Body Iron Stores and the Risk of CancerNew England Journal of Medicine, 1988
- Requirement for c-ras proteins during viral oncogene transformationNature, 1986