PERFORMANCE EVALUATION OF SPRINT, A SINGLE PHOTON RING TOMOGRAPH FOR BRAIN IMAGING

  • 1 January 1984
    • journal article
    • research article
    • Vol. 25  (9) , 1013-1018
Abstract
SPRINT, a prototype single photon tomograph, was designed primarily for high-resolution brain imaging in humans with 123I-labeled compounds such as iodoamphetamine, hydroxyiodopropyldiamine (HIPDM), and iodobenzene (IBZ). SPRINT uses a ring of stationary, discrete NaI detectors, and fan-beam sampling is accomplished with a rotating 8-slit aperture ring that acquires a complete projection set in 1/8 revolution. In-plane and cross-plane resolutions are 8 and 10 mm FWHM [full width-half maximum], respectively, measured on axis. Sensitivity with an 18% energy window is 1000 cprs per .mu.Ci/cm3 for 99mTc in a 20 cm diameter phantom. A detailed evaluation of system performance was completed, and preliminary human brain blood flow images were obtained using HIPDM.