Pathogenesis and Prognosis of Prematurity

Abstract
Cerebral PalsyThe frequent association between prematurity and cerebral palsy has been known since Little's classic monograph in 1861. Thirty-two years later Sigmund Freud, then primarily interested in neurology, suggested that since cerebral palsy does not develop in all premature infants, perhaps some unknown process produced both prematurity and cerebral palsy. Seventy-two years later there is still no evidence to refute this hypothesis.The incidence of cerebral palsy is 5.9 per 1000 live births in the United States and 1.9 per 1000 in Norway. Differences in reporting and criteria for diagnosis could be partly responsible for this discrepancy, but European . . .

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