Gene-sized DNA molecules of the Oxytricha macronucleus have the same terminal sequence.
- 1 October 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (10) , 4325-4328
- https://doi.org/10.1073/pnas.74.10.4325
Abstract
The DNA in the macronucleus of the ciliated protozoan Oxytricha exists as small linear molecules with a number average size of about 3000 base pairs. Most, and possibly all of these DNA molecules contain the same inverted terminal repeat sequence of approximately 26 base pairs. In addition to its terminal location, 2 inverted copies of this same sequence surround single-strand interruptions within these DNA molecules. This sequence arrangement may function in the processing of these molecules from large chromosomal precursors or in the subsequent replication of these small linear DNA during cell reproduction.Keywords
This publication has 16 references indexed in Scilit:
- Translocatable elements in procaryotesCell, 1977
- Sequence arrangement of the rDNA of Drosophila melanogasterCell, 1977
- Enzymatic in vitro synthesis of globin genesCell, 1976
- Polytene chromosomes of Oxytricha: Biochemical and morphological changes during macronuclear development in a ciliated protozoanChromosoma, 1976
- Restriction EndonucleaseCRC Critical Reviews in Biochemistry, 1976
- DNA of ciliated protozoa: DNA sequence diminution during macronuclear development of oxytrichaCell, 1976
- Palindromic base sequences and replication of eukaryote chromosome endsNature, 1974
- A fast method of analysis of the 5′ terminal nucleotides of deoxyribooligonucleotidesAnalytical Biochemistry, 1974
- Chromosome Structure in Ciliated ProtozoansPublished by Cold Spring Harbor Laboratory ,1974
- Genetic Apparatus of Stylonychia sp.Nature, 1973