Post-streptococcal Glomerulonephritis Following Pyoderma
- 1 November 1979
- journal article
- review article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 1 (6) , 935-945
- https://doi.org/10.1093/clinids/1.6.935
Abstract
Studies of the epidemiology of acute glomerulonephritis (AGN) following pyoderma reported over the past 15 years have been reviewed. Investigations in Alabama at Red Lake in Minnesota, and in Trinidad proved of special interest because they contribute new information concerning the natural history of streptococcal skin infections and the role of such infections in AGN. Interesting contrasts between streptococcal infections of the skin and those of the throat are now apparent. Compared with pharyngeal infections, skin infections are more common in young preschool children, are caused by different serotypes, and differ in the nature of the streptococcal antibody response. A number of new M-serotypes of group A streptococci, including several of importance in AGN, were found in studies of pyoderma. In contrast to M-types 1 and 12(those of major jor importance in AGN following pharyngitis), M-types 2, 49, 55, 57, and 60 are now recognized to be of .major importance in AGN following pyoderma. Although streptococcal skin infections are quite important in AGN, they do not result in acute rheumatic fever.Keywords
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