Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer
- 1 March 2006
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 42 (5) , 597-607
- https://doi.org/10.1086/500139
Abstract
Background. Gram-positive pathogens can cause serious infections in neutropenic patients with cancer, and vancomycin therapy is often initiated empirically. Linezolid may offer an option for these patients.Keywords
This publication has 21 references indexed in Scilit:
- Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumoniaClinical Therapeutics, 2003
- Linezolid versus Vancomycin for the Treatment of Methicillin‐ResistantStaphylococcus aureusInfectionsClinical Infectious Diseases, 2002
- 2002 Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with CancerClinical Infectious Diseases, 2002
- Linezolid (PNU-100766) versus Vancomycin in the Treatment of Hospitalized Patients with Nosocomial Pneumonia: A Randomized, Double-Blind, Multicenter StudyClinical Infectious Diseases, 2001
- Emergence of Vancomycin Resistance inStaphylococcus aureusNew England Journal of Medicine, 1999
- Outcomes of Bacteremia in Patients with Cancer and Neutropenia: Observations from Two Decades of Epidemiological and Clinical TrialsClinical Infectious Diseases, 1997
- Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibilityJournal of Antimicrobial Chemotherapy, 1997
- Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial InfectionsJournal of Medicinal Chemistry, 1996
- Trends in bacterial infections in febrile neutropenic patients: 1986–1992Australian and New Zealand Journal of Medicine, 1994
- Vancomycin, Ticarcillin, and Amikacin Compared with Ticarcillin-Clavulanate and Amikacin in the Empirical Treatment of Febrile, Neutropenic Children with CancerNew England Journal of Medicine, 1988