Immunoglobulins and Other Serum Proteins in Feces from Infants and Children

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Abstract
IgA in variable amounts was found in extracts of feces from all of 14 infants and children with no apparent diseases involving the gastrointestinal tract or the immune system, whereas IgG and IgM were only found in some. No age variation was evident's even one‐month‐old infants seemed fully able to secrete intestinal immunoglobulins. Freeze‐drying of the feces facilitated the extraction, and the amounts of immunoglobulins were related to the dry weight of fecas. Most of the immunoglobulins were easily dissolved in saline. Of other serum proteins α1 antitrypsin was constantly present; α1 antichymotrypsin and α2 macroglobulin were found in many. Only traces of albumin were sometimes demonstrated.