THE EFFECT OF EXERCISE ON THE CONCENTRATION AND TURNOVER OF PLASMA NONESTERIFIED FATTY ACIDS*

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Abstract
Acute exercise accelerates the turnover rate of plasma free fatty acids in man. Arterial albumin-bound fatty acids (FFA) concentration fell promptly by an average of 26% during 15 minutes of exercise and rose significantly above resting levels afterwards. Fatty acids were determined by the method of Dole, modified to remove lactic acid. The fall in total concentration of FFA was accompanied by an accelerated disappearance of intravenously injected palmitic acid-l-C, with plasma half life decreasing from an average of 2.4 to 1.5 minutes. From these data there is a calculated minimal increase in plasma FFA flux of 25% during exercise.