Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli
- 29 February 2008
- journal article
- Published by Elsevier in Protein Expression and Purification
- Vol. 57 (2) , 188-200
- https://doi.org/10.1016/j.pep.2007.10.010
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Science and Technology, Pakistan (MG05-0309-5-0)
- National Research Foundation of Korea (KRF-C0081)
- Ministry of Education and Human Resources Development
- U.S. Public Health Service (P30 ES00267, R37 CA090426)
This publication has 36 references indexed in Scilit:
- Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2Journal of Biological Chemistry, 2007
- Functional Expression of Human Cytochrome P450 Enzymes in Escherichia coliCurrent Drug Metabolism, 2006
- Summary of information on human CYP enzymes: human P450 metabolism dataDrug Metabolism Reviews, 2002
- Rate-Determining Steps in Phenacetin Oxidations by Human Cytochrome P450 1A2 and Selected MutantsBiochemistry, 2000
- New Applications of Bacterial Systems to Problems in ToxicologyCritical Reviews in Toxicology, 1996
- Expression of Modified Human Cytochrome P450 1A2 in Escherichia coli: Stabilization, Purification, Spectral Characterization, and Catalytic Activities of the EnzymeArchives of Biochemistry and Biophysics, 1994
- Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.Environmental Health Perspectives, 1992
- High‐level expression of functional human cytochrome P450 1A2 in Escherichia coliThe FASEB Journal, 1992
- The Human Hepatic Cytochromes P450 Involved in Drug MetabolismCritical Reviews in Toxicology, 1992
- Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.Proceedings of the National Academy of Sciences, 1989