Shared antigenic determinants between human brain and human T-cell line.
- 1 December 1974
- journal article
- Vol. 18 (4) , 491-8
Abstract
Rabbits were immunized with MOLT cells (T cells) and RPMI number 1788 (B cells) to get respective antisera. These sera were absorbed with human liver, human brain, or various B cells (RPMI number 1788, SOMMER-B cell, B-35M cells and B-411 cells). The results indicate that the cytotoxicity of rabbit anti-MOLT serum against MOLT cells could be absorbed to some extent with human liver and various B cells but not completely. Human brain could completely absorb anti-MOLT activity from rabbit anti-MOLT serum. Human brain could not remove anti-B-cell activity from rabbit anti-RPMI number 1788 (B cells). Rat brain did not remove anti-MOLT activity from anti-MOLT serum.This publication has 15 references indexed in Scilit:
- THYMUS-SPECIFIC ANTIGENS ON HUMAN THYMOCYTES AND ON THYMIC-DERIVED LYMPHOCYTESTransplantation, 1973
- Rosette-Forming Human Lymphoid Cell Lines. I. Establishment and Evidence for Origin of Thymus-Derived Lymphocytes2JNCI Journal of the National Cancer Institute, 1972
- SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTESThe Journal of Experimental Medicine, 1972
- Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell linesJournal of Clinical Investigation, 1972
- TISSUE- AND SPECIES-SPECIFIC ANTIBODIES IN ANTITHYMOCYTE GLOBULINTransplantation, 1972
- Surface-bound Immunoglobulin as a Marker of B Lymphocytes in ManNature New Biology, 1971
- Selective gene action in the specification of cell surface structure.1971
- IDENTIFICATION OF HUMAN T AND B LYMPHOCYTES IN NORMAL PERIPHERAL BLOOD AND IN CHRONIC LYMPHOCYTIC LEUKÆMIAThe Lancet, 1971
- Brain-associated Θ antigen: Reactivity of rabbit anti-mouse brain with mouse lymphoid cellsCellular Immunology, 1971
- Binding of Sheep Red Blood Cells to a Large Population of Human LymphocytesNature, 1971