Stereochemistry of the conversion of serine and tyrosine into pyruvate by tyrosine phenol-lyase

Abstract
(2S,3R)- and (2S,3S)-[3-3H]serine in D2O and (2S,3R)-[3-2H]tyrosine in HTO were incubated with tyrosine phenol-lyase to give pyruvate which was trapped as lactate; chirality analysis of the methyl group in the products showed that the replacement of the β-substituent in these amino acids by hydrogen had occurred stereospecifically with retention of configuration.

This publication has 0 references indexed in Scilit: