Artifactual Isoform Profile Modification Following Treatment of Human Plasma or Serum with Protease Inhibitor, Monitored by 2-Dimensional Electrophoresis and Mass Spectrometry
Open Access
- 1 August 2005
- journal article
- research article
- Published by Taylor & Francis in BioTechniques
- Vol. 39 (2) , 239-247
- https://doi.org/10.2144/05392rr01
Abstract
The inclusion of protease inhibitors in serum or plasma samples has been found to significantly impact the isoform profile of selected plasma proteins as seen on 2-dimensional electrophoresis (2-DE) gels. With the addition of a...Keywords
Funding Information
- Sigma-Aldrich Corporation
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