Autologous stem cell transplantation in a lymphoma patient with a long history of ankylosing spondylitis
Open Access
- 1 May 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 39 (5) , 563-564
- https://doi.org/10.1093/rheumatology/39.5.563
Abstract
Sir, Based on animal studies and anecdotal human data, high‐dose chemotherapy supported by stem cell transplantation (SCT) has been recently suggested as an experimental therapy in patients with various autoimmune diseases [1, 2]. While allogeneic SCT performed for another reason may lead to an apparent cure in some patients with concomitant rheumatic diseases [3], experience has been less promising in the case of autologous SCT (ASCT) [4, 5]. ASCT has recently been performed in about 140 patients solely on the grounds of severe or therapy‐resistant autoimmune disease [6]. Although a number of transplants have been performed in patients with systemic sclerosis, systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA), there are no reports on the effects of ASCT in patients with ankylosing spondylitis (AS).Keywords
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