L-Histidine-Induced Hypercholesterolemia: Characteristics of Cholesterol Biosynthesis in Rat Livers
- 1 October 1978
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 159 (1) , 44-46
- https://doi.org/10.3181/00379727-159-40280
Abstract
A diet supplemented 5% with L-histidine caused a 100% increase in the incorporation of [2-14C] acetate or [1-14C] octanoate into cholesterol in liver slices of weanling rats after 4 days of feeding. The incorporation of the labeled substrates into triglycerides decreased 38%. The hepatic DNA-to-protein ratio decreased 19% with histidine feeding, suggesting an increase in hepatocyte size.This publication has 1 reference indexed in Scilit:
- Hyperlipemia in Infant Monkeys Fed Excess L-Histidine.Experimental Biology and Medicine, 1965