Placebo-responsive Parkinson patients show decreased activity in single neurons of subthalamic nucleus
Open Access
- 16 May 2004
- journal article
- research article
- Published by Springer Nature in Nature Neuroscience
- Vol. 7 (6) , 587-588
- https://doi.org/10.1038/nn1250
Abstract
Placebo administration is known to affect the brain both in pain and in Parkinson disease. Here we show that placebo treatment caused reduced activity in single neurons in the subthalamic nucleus of placebo-responsive Parkinsonian patients. These changes in activity were tightly correlated with clinical improvement; no decrease in activity occurred when the clinical placebo response was absent.Keywords
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