Catecholamine Levels and Their Correlation to Blood Gases in Umbilical Venous Blood Obtained by Cordocentesis

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Abstract
The plasma catecholamine concentration was evaluated in umbilical venous blood obtained by cordocentesis performed in 77 fetuses for indications including: nonimmune hydrops; Rh incompatibility; intrauterine growth retardation; polyhydramnios; anomalies; immunological disorders, and possible viral infection. The pH as well as pO2 of the umbilical venous blood showed a notably significant negative correlation with the norepinephrine concentration (r = ––0.5607, r = ––0.4467); while pCO2 was also significantly correlated with the norepinephrine concentration (r = 0.4955). When the pCO2/pO2 ratio was tentatively put up for comparison, the ratio was undoubtedly better correlated (r = 0.60442) with the fetal norepinephrine concentration than any other biochemical variable. Moreover, the ratio over 2.0 suggests that fetal catecholamine values have reached abnormal levels.

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