The Condensation of DNA by Chromium (III) Ions
- 1 October 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Biomolecular Structure and Dynamics
- Vol. 2 (2) , 285-290
- https://doi.org/10.1080/07391102.1984.10507567
Abstract
Cr(III), one of the most potent inorganic carcinogens, induces condensation of DNA into a very compact product at 37°, as shown by electron microscopy. The condensation begins with the appearing of some supercoil structures and complete condensation occurs at relatively low Cr(III) concentrations; for 3 and 30 mM ionic strength they are 4.5 and 45 μM, respectively. Under these conditions, Cr(III) inhibits the interaction between ethidium and DNA as shown by absorption and fluorescence spectra.This publication has 12 references indexed in Scilit:
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