Quantitative Densitometric Determination of Theophylline
- 1 April 1989
- journal article
- analytical biochemistry-and-clinical-analysis
- Published by Taylor & Francis in Analytical Letters
- Vol. 22 (4) , 827-839
- https://doi.org/10.1080/00032718908051370
Abstract
A method for identification and quantification of theophylline in certain dosage forms, that employs TLC-scanner is reported. the method is applied for theophylline either as raw material or in certain dosage forms admixed with other medicamenta. Samples were extracted with methanol, separated and measured in situ on silica gel G plates at about 270 nm using TLC-scanner. the mean recovery (six determinations) was 99.9± 0.57. the developed procedure has been found to be simple, rapid and precise and its application to various dosage forms was demonstrated and yields comparable results with UV measurement after location, scraping and elution from the plates.Keywords
This publication has 0 references indexed in Scilit: