A Case of the Hand‐Schüller‐Christian Disease Treated with Cortisone1 (A Discussion of the Primary or Secondary Nature of the Lipold Deposits)

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Abstract
Summary: Report of an 1 1/2 year old boy with Hand‐Schüller‐Christian disease. A dose of 3 mg cortisone per kg of body weight per day, injected intramuscularly, initially resulted in conspicuous improvement. Thus, the general condition improved, the hepatomegaly and splenomegaly decreased, as did the protrusion of the eyeball, polyruia and polydipsia. Oedema subsequently developed and became increasingly severe; no changes were found in the blood chemistry to account for it. It was necessary to discontinue cortisone therapy after 3 weeks. The patient's condition deteriorated rapidly and he died after a further 5 days.

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