Contemporary Management of Superficial Bladder Cancer
Open Access
- 1 July 2000
- journal article
- research article
- Published by SAGE Publications in Cancer Control
- Vol. 7 (4) , 335-339
- https://doi.org/10.1177/107327480000700402
Abstract
Background: Bladder cancer is the second most common urologic malignancy after prostate cancer. Superficial bladder cancer presents as a heterogeneous group of tumors with variable biological potential. A significant percentage of patients diagnosed with superficial cancer will have multiple recurrences, and some will progress to invasive disease. Methods: Patients are stratified into low- or high-risk for recurrence and progression. We review the most recent literature regarding intravesical therapy for superficial bladder cancer, and we summarize indications for the use of intravesical agents as well as their efficacy, toxicity, and cost. Results: Several intravesical agents are available for the treatment of superficial bladder cancer. Patients may be identified as low- or high-risk for recurrence and progression. High-risk patients benefit from intravesical therapy. Conclusions: Superficial bladder cancer is a heterogeneous group of diseases. Treatment is effective in preventing recurrences and progression in the high-risk group.Keywords
This publication has 18 references indexed in Scilit:
- MAINTENANCE BACILLUS CALMETTE-GUERIN IMMUNOTHERAPY FOR RECURRENT TA, T1 AND CARCINOMA IN SITU TRANSITIONAL CELL CARCINOMA OF THE BLADDER: A RANDOMIZED SOUTHWEST ONCOLOGY GROUP STUDYJournal of Urology, 2000
- EFFICACY AND SAFETY OF VALRUBICIN FOR THE TREATMENT OF BACILLUS CALMETTE-GUERIN REFRACTORY CARCINOMA IN SITU OF THE BLADDERJournal of Urology, 2000
- AN OVERVIEW OF THE TREATMENT OF SUPERFICIAL BLADDER CANCER: Intravesical ChemotherapyUrologic Clinics of North America, 2000
- EXCLUSION CRITERIA ENHANCE THE SPECIFICITY AND POSITIVE PREDICTIVE VALUE OF NMP22* AND BTA STAT [dagger]Journal of Urology, 1999
- EFFECTIVENESS OF A SINGLE IMMEDIATE MITOMYCIN C INSTILLATION IN PATIENTS WITH LOW RISK SUPERFICIAL BLADDER CANCER: SHORT AND LONG-TERM FOLLOWUPJournal of Urology, 1999
- Tumour progression and survival in patients with T1G3 bladder tumours: 15‐year outcomeBritish Journal of Urology, 1997
- Initial report on intraves1cal administration of N-trifluoroacetyladriamycin-14-valerate (AD 32) to patients with refractory superficial transitional cell carcinoma of the urinary bladderUrology, 1997
- Bacillus calmette-Guérin plus intravesical interferon alpha-2b in patients with superficial bladder cancerUrology, 1996
- The Effect of Intravesical Mitomycin C on Recurrence of Newly Diagnosed Superficial Bladder Cancer: A Further Report with 7 Years of FollowupJournal of Urology, 1996
- Frequency and nature of cutaneous reactions to intravesical instillation of mitomycin for superficial bladder cancerUrology, 1992