CHEMOPROPHYLAXIS OF CRYPTOSPORIDIOSIS IN CHICKENS, USING HALOFUGINONE, SALINOMYCIN, LASALOCID, OR MONENSIN

  • 1 March 1987
    • journal article
    • research article
    • Vol. 48  (3) , 354-355
Abstract
Chemoprophylaxis of Cryptosporidium baileyi infections was attempted by feeding 4 groups of chicks diets containing 3 mg of halofuginone/kg of feed, 60 mg of salinomycin/kg, 75 mg of lasalocid/kg, or 110 mg of monensin/kg. Rations were fed 5 days before oral or intratracheal inoculation with oocytes and we continued for 20 days None of the drugs prevented C. baileyi infections. Clinical signs of respiratory tract disease and gross lesions of air sacculitis were observed in intratracheally inoculated birds in all treatment groups and nonmediated controls. Orally inoculated birds did not develop clinical signs of infection. Pathogentic bacteria were not isolated from the respiratory tract systems of any chicks. Halofuginone delayed the establishment of infections of the bursa of Fabricius and cloaca, but not of the trachea.

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