Metabolic Regulation of Potassium Channels
- 1 March 2004
- journal article
- review article
- Published by Annual Reviews in Annual Review of Physiology
- Vol. 66 (1) , 131-159
- https://doi.org/10.1146/annurev.physiol.66.041002.142720
Abstract
Potassium (K+) channels exist in all three domains of organisms: eubacteria, archaebacteria, and eukaryotes. In higher animals, these membrane proteins participate in a multitude of critical physiological processes, including food and fluid intake, locomotion, stress response, and cognitive functions. Metabolic regulatory factors such as O2, CO2/pH, redox equivalents, glucose/ATP/ADP, hormones, eicosanoids, cell volume, and electrolytes regulate a diverse group of K+ channels to maintain homeostasis.Keywords
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