Clinically Undetected Motor Neuron Disease in Pathologically Proven Frontotemporal Lobar Degeneration With Motor Neuron Disease

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Abstract
Frontotemporal dementia (FTD) is a clinical term applied to patients who present with progressive dementia with an insidious onset, prominent behavioral or language dysfunction, or both. Motor neuron disease (MND) is also a clinical term, but it is applied to patients with clinical evidence of corticospinal tract involvement, evidence of brainstem or spinal cord anterior horn cell involvement, or both. Recent studies have revealed that clinical features of FTD and MND (FTD-MND) can occur in the same patient and not infrequently.1-3